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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PRMT5, protein arginine methyltransferase 5
Sequence ID:NM_001039619
NM_006109
Entrez Gene ID:10419
Ensembl ID:ENSG00000100462

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 23390113 - 23398570

 Exon Info From UCSC:
NM_001039619
NM_006109

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3833019Full LengthBC025979protein arginine methyltransferase 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006100  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001039619 NP_001034708      
NM_006109 NP_006100 O14744 EC 2.1.1.125 PRMT5

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF015913 AAB66581 O14744 EC 2.1.1.125
AF167572 AAF04502 O14744 EC 2.1.1.125
BC025979 AAH25979 O14744 EC 2.1.1.125
DQ893421 ABM84347    
DQ896773 ABM87772    
AK315500 BAG37884 B2RDD7  
AK075251 BAG52095 O14744 EC 2.1.1.125
AK300863 BAG62512 B4DV00  
AK301812 BAG63261 B4DX49  
AK302240 BAG63592 B4DY30  
AB451246 BAG70060 O14744 EC 2.1.1.125
AB451370 BAG70184 O14744 EC 2.1.1.125
CR456741 CAG33022 O14744 EC 2.1.1.125

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PRMT5 NP_006100 M.musculus Prmt5 27374 Gene Info NP_038796 98
R.norvegicus Prmt5 364382   NP_001102337 98
A.thaliana SKB1 829240   NP_194841 50
A.gambiae AgaP_AGAP009048 1280006   XP_319800 46
D.melanogaster csul 36809   NP_477184 42
S.pombe skb1 2540099   NP_595936 39
N.crassa NCU01613 3872672   XP_956524 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)