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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. U2AF1, U2 small nuclear RNA auxiliary factor 1
Sequence ID:NM_001025203
RefSeqGene ID:NG_029455
Entrez Gene ID:7307
Ensembl ID:ENSG00000160201

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 44513213 - 44527604

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823296Full LengthBC001923U2 small nuclear RNA auxiliary factor 1
3534272Full LengthBC001177U2 small nuclear RNA auxiliary factor 1
4295037Full LengthBC005915U2 small nuclear RNA auxiliary factor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006749  NP_001020375  NP_001020374  

Protein Infomation

NM_001025203 NP_001020374   RRM_1
NM_001025204 NP_001020375   RRM_1
NM_006758 NP_006749 Q01081 RRM_1

Related Sequences

M96982 AAA36619 Q01081
BC001177 AAH01177 Q01081
BC001923 AAH01923 Q01081
BC005915 AAH05915 Q7Z780
AF370386 AAQ15222 Q01081
HQ447764 ADQ32249  
AB451244 BAG70058 B5BU08
AJ627978 CAF29556 Q01081
AL832665 CAH10401 Q69YM7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens U2AF1 NP_006749 M.musculus U2af1 108121 Gene Info NP_077149 100
A.gambiae AgaP_AGAP002956 1273007   XP_311943 79
D.melanogaster U2af38 33201   NP_477208 79
C.elegans uaf-2 178489   NP_503036 64
S.pombe SPAP8A3.06 2542482   NP_594945 61
N.crassa NCU03261 3880563   XP_964414 59
A.thaliana ATU2AF35A 839657   NP_174086 58
A.thaliana U2AF35B 834293   NP_199096 56
P.falciparum PF11_0200 810747   XP_001347871 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta