Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CFH, complement factor H
Sequence ID:NM_000186
NM_001014975
RefSeqGene ID:NG_007259
Entrez Gene ID:3075
Ensembl ID:ENSG00000000971

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BASAL LAMINAR DRUSEN 
COMPLEMENT FACTOR H DEFICIENCY 
HEMOLYTIC UREMIC SYNDROME, ATYPICALCD46
CFHR1
CFHR3
CFI
MACULAR DEGENERATION, AGE-RELATED, 4FKBP10

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 196667324 - 196669783

 Exon Info From UCSC:
NM_000186
NM_001014975

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40148771Full LengthBC142699complement factor H
3996233IncompleteBC012610complement factor H

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001014975  NP_000177  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000186 NP_000177 P08603 Sushi
NM_001014975 NP_001014975   Sushi

Related Sequences

 
mRNAGenPeptSwissProt
M65294 AAA35948 P08603
M12383 AAA52013 P08603
M17517 AAA52016 Q14006
BC037285 AAH37285 P08603
BC110643 AAI10644 P08603
BC142699 AAI42700 P08603
JF432152 ADZ15369  
AK291395 BAF84084 A8K5T0
X07523 CAA30403 P08603
Y00716 CAA68704 P08603
X04697 CAB41739 P08603

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CFH NP_000177 R.norvegicus Cfh 155012   NP_569093 64
M.musculus Cfh 12628 Gene Info NP_034018 62

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)