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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PPIA, Peptidylprolyl isomerase A (cyclophilin A)
Sequence ID:NM_021130
RefSeqGene ID:NG_029697
Entrez Gene ID:5478
Ensembl ID:ENSG00000196262

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 44836323 - 44841021

NM_021130 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11524483624044836391
1531834483884544838875
1842724483899044839078
2734454483930044839472
44622754484088544842714

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823490Full LengthBC003026peptidylprolyl isomerase A (cyclophilin A)
2986147Full LengthBC106030peptidylprolyl isomerase A (cyclophilin A)
3349335Full LengthBC000689peptidylprolyl isomerase A (cyclophilin A)
3684721Full LengthBC013915peptidylprolyl isomerase A (cyclophilin A)
3935025Full LengthBC005320peptidylprolyl isomerase A (cyclophilin A)
4109260Full LengthBC005982peptidylprolyl isomerase A (cyclophilin A)
4281376Full LengthBC007104peptidylprolyl isomerase A (cyclophilin A)
6161389Full LengthBC073992peptidylprolyl isomerase A (cyclophilin A)
9021054Full LengthBC137057peptidylprolyl isomerase A (cyclophilin A)
9021055Full LengthBC137058peptidylprolyl isomerase A (cyclophilin A)
30414589Full LengthBC093076peptidylprolyl isomerase A (cyclophilin A)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_066953  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_021130 NP_066953 P62937 EC 5.2.1.8 Pro_isomerase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC000689 AAH00689 P62937 EC 5.2.1.8
BC003026 AAH03026 P62937 EC 5.2.1.8
BC005320 AAH05320 P62937 EC 5.2.1.8
BC005982 AAH05982 P62937 EC 5.2.1.8
BC007104 AAH07104 P62937 EC 5.2.1.8
BC013915 AAH13915 P62937 EC 5.2.1.8
BC073992 AAH73992 P62937 EC 5.2.1.8
BC093076 AAH93076 Q567Q0  
BC106030 AAI06031 P62937 EC 5.2.1.8
BC137057 AAI37058 P62937 EC 5.2.1.8
BC137058 AAI37059 P62937 EC 5.2.1.8
DQ892625 ABM83551    
DQ895865 ABM86791    
D28351 BAA05717    
AK290085 BAF82774 P62937 EC 5.2.1.8
AK290851 BAF83540 A8K486  
AK293003 BAF85692 Q567Q0  
AK316564 BAG38153 B2RE56  
AK297340 BAG59794 B4DM82  
AB451307 BAG70121 P62937 EC 5.2.1.8
AB451438 BAG70252 P62937 EC 5.2.1.8
Y00052 CAA68264 P62937 EC 5.2.1.8
CR456707 CAG32988 P62937 EC 5.2.1.8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PPIA NP_066953 R.norvegicus Ppia 25518   NP_058797 96
M.musculus Ppia 268373 Gene Info NP_032933 96
R.norvegicus LOC100360977 100360977   XP_002728136 96
R.norvegicus LOC100362969 100362969   XP_002729493 96
D.melanogaster CG7768 39573   NP_729966 75
A.thaliana ROC5 829639   NP_195213 73
A.thaliana ROC3 816161   NP_179251 72
A.thaliana ROC1 830029   NP_195585 71
C.elegans cyn-7 180027   NP_506749 71
A.thaliana AT2G21130 816648   NP_179709 70
C.elegans cyn-3 180028   NP_506751 70
C.elegans cyn-2 176807   NP_499828 69
P.falciparum PfCyP19 814534   XP_001351290 64

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta