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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. POR, P450 (cytochrome) oxidoreductase
Sequence ID:NM_000941
RefSeqGene ID:NG_008930
Entrez Gene ID:5447
Ensembl ID:ENSG00000127948

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ANTLEY-BIXLER SYNDROME WITH GENITAL ANOMALIES AND DISORDEREDSTEROIDOGENESIS 
DISORDERED STEROIDOGENESIS DUE TO CYTOCHROME P450 OXIDOREDUCTASE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 75583319 - 75615799

 Exon Info From UCSC:
NM_000941

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3882411Full LengthBC034277P450 (cytochrome) oxidoreductase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000932  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000941 NP_000932   NAD_binding_1
Flavodoxin_1
FAD_binding_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S90469 AAB21814 P16435 EC 1.6.2.4
AF258341 AAG09798 P16435 EC 1.6.2.4
BC034277 AAH34277 P16435 EC 1.6.2.4
AB051763 BAB18572 P16435 EC 1.6.2.4
AB209874 BAD93111 Q59ED7  
AK290529 BAF83218 A8K3B4  
AK312543 BAG35442 B2R6E5  
AK293194 BAG56734 B4DDH3  
AK296096 BAG58850 B4DJI8  
AK296639 BAG59240 B4DKM8  
AK304511 BAG65317 B4E305  
BX648619 CAH56151 Q63HL4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens POR NP_000932 R.norvegicus Por 29441   NP_113764 93
M.musculus Por 18984 Gene Info NP_032924 92
D.melanogaster Cpr 33883   NP_477158 58
C.elegans emb-8 175710   NP_498103 50
A.gambiae AgaP_AGAP000500 1271741   XP_310593 48
A.thaliana ATR1 828554   NP_194183 42
S.pombe ccr1 2541038   NP_596046 40
N.crassa NCU09741 3880583   XP_964443 39
S.cerevisiae NCP1 856438   NP_011908 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta