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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TAP1, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Sequence ID:NM_000593
RefSeqGene ID:NG_011759
Entrez Gene ID:6890
Ensembl ID:ENSG00000168394

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pineal gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
BARE LYMPHOCYTE SYNDROME, TYPE ITAP2
TAPBP

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 32813355 - 32821413

 Exon Info From UCSC:
NM_000593

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4304716Full LengthBC014081transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000584  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000593 NP_000584 Q03518 ABC_tran
ABC_membrane

Related Sequences

 
mRNAGenPeptSwissProt
L21204 AAC12902 Q03518
L21205 AAC12903 Q6QWC0
Q03518
L21206 AAC12904 Q6QWC0
Q03518
L21207 AAC12905 Q03518
L21208 AAC12906 Q03518
S70256 AAD14054 Q53WZ1
S70266 AAD14055 Q16148
S70274 AAD14056 Q03518
BC014081 AAH14081 Q03518
AY523970 AAS55411 Q6QWC1
AY523971 AAS55412 Q6QWC0
DQ896350 ABM87349  
EU176425 ABW03876  
AB012644 BAA32813 O94774
AK313762 BAG36500 B2R9F3
AK302340 BAH13680 B7Z7P4
X57521 CAA40740 Q03518
X57522 CAA40741 Q03518

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TAP1 NP_000584 M.musculus Tap1 21354 Gene Info NP_038711 73
R.norvegicus Tap1 24811   NP_114444 72

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta