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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SOST, sclerostin
Sequence ID:NM_025237
RefSeqGene ID:NG_008078
Entrez Gene ID:50964
Ensembl ID:ENSG00000167941

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CRANIODIAPHYSEAL DYSPLASIA, AUTOSOMAL DOMINANT 
SCLEROSTEOSIS 
VAN BUCHEM DISEASE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 41831105 - 41832563

NM_025237 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
2320554183109841833130
205623224183588941836155

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40009481Full LengthBC101086sclerosteosis
40009482Full LengthBC101087sclerosteosis
40009485Full LengthBC101088sclerosteosis
40009488Full LengthBC101089sclerosteosis

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_079513  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_025237 NP_079513 Q9BQB4 Sclerostin

Related Sequences

 
mRNAGenPeptSwissProt
BC101086 AAI01087 Q9BQB4
BC101087 AAI01088 Q9BQB4
BC101088 AAI01089 Q9BQB4
BC101089 AAI01090 Q9BQB4
AF326739 AAK13454 Q9BQB4
AF331844 AAK16158 Q9BQB4
AF170491 AAQ13601 Q7Z4G0
AF184211 AAQ13694 Q7Z2R3
AY358203 AAQ88570 Q9BQB4
AY358627 AAQ88990 Q9BQB4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SOST NP_079513 R.norvegicus Sost 80722   NP_085073 90
M.musculus Sost 74499 Gene Info NP_077769 88

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)