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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. DR1, down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Sequence ID:NM_001938
Entrez Gene ID:1810
Ensembl ID:ENSG00000117505

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 93811491 - 93826725

NM_001938 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3634908Full LengthBC002809down-regulator of transcription 1, TBP-binding (negative cofactor 2)
4555131Full LengthBC035507down-regulator of transcription 1, TBP-binding (negative cofactor 2)
4822070Full LengthBC068553down-regulator of transcription 1, TBP-binding (negative cofactor 2)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001929  

Protein Infomation

NM_001938 NP_001929 Q658N3

Related Sequences

M97388 AAA58442 Q658N3
BC002809 AAH02809 Q658N3
BC035507 AAH35507 Q658N3
BC068553 AAH68553 Q658N3
BT006972 AAP35618 Q658N3
AK223442 BAD97162 Q53F47
AK057541 BAG51931 Q658N3
AL833729 CAH56250 Q658N3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens DR1 NP_001929 M.musculus Dr1 13486 Gene Info NP_080382 99
R.norvegicus Dr1 289881   NP_001011914 99
A.gambiae AgaP_AGAP010322 1278624   XP_318244 64
D.melanogaster NC2beta 34875   NP_609736 61
S.pombe SPBC30D10.02 2540406   NP_596283 50
N.crassa NCU02017 3881031   XP_964882 47
A.thaliana NF-YB12 830715   NP_568190 45
C.elegans dro-1 191629   NP_499750 45
A.thaliana NF-YB13 832373   NP_851060 43
S.cerevisiae NCB2 852006   NP_010685 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)