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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MTOR, mechanistic target of rapamycin (serine/threonine kinase)
Sequence ID:NM_004958
Entrez Gene ID:2475
Ensembl ID:ENSG00000198793

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 11166592 - 11322589

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40125717Full LengthBC117166FK506 binding protein 12-rapamycin associated protein 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004949  

Protein Infomation

NM_004958 NP_004949 P42345 EC PI3_PI4_kinase

Related Sequences

L34075 AAA58486 P42345 EC
U88966 AAC39933 P42345 EC
L35478 AAC41713 P42345 EC
BC117166 AAI17167 P42345 EC
AB209995 BAE06077 P42345 EC
AK126762 BAG54371 B3KX59  
AK302863 BAG64047 B4DZD5  
AK304273 BAG65134 B4E2H2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MTOR NP_004949 M.musculus Mtor 56717 Gene Info NP_064393 99
R.norvegicus Mtor 56718   NP_063971 99
A.gambiae AgaP_AGAP007873 1278082   XP_317619 57
D.melanogaster Tor 47396   NP_524891 57
S.pombe tor1 2540473   NP_596275 47
S.cerevisiae TOR2 853632   NP_012719 46
A.thaliana TOR 841427   NP_175425 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta