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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. FDPS, farnesyl diphosphate synthase
Sequence ID:NM_001135821
NM_001135822
NM_001242824
NM_001242825
NM_002004
Entrez Gene ID:2224
Ensembl ID:ENSG00000160752

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 155278737 - 155290456

 Exon Info From UCSC:
NM_001135821
NM_001135822
NM_002004

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4132071Full LengthBC010004farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001995  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001135821 NP_001129293      
NM_001135822 NP_001129294      
NM_001242824 NP_001229753      
NM_001242825 NP_001229754      
NM_002004 NP_001995 P14324 EC 2.5.1.10
EC 2.5.1.1
polyprenyl_synt

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M29863 AAA35820 P14324 EC 2.5.1.10
EC 2.5.1.1
J05262 AAA52423 P14324 EC 2.5.1.10
EC 2.5.1.1
BC010004 AAH10004 P14324 EC 2.5.1.10
EC 2.5.1.1
DQ893471 ABM84397    
DQ895943 ABM86869    
D14697 BAA03523 P14324 EC 2.5.1.10
EC 2.5.1.1
AK291084 BAF83773 P14324 EC 2.5.1.10
EC 2.5.1.1
AK022841 BAG51125 B3KMW3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FDPS NP_001995 R.norvegicus Fdps 83791   NP_114028 85
M.musculus Fdps 110196 Gene Info NP_608219 84
S.pombe fps1 2542898   NP_593299 52
N.crassa NCU01175 3877737   XP_961541 49
D.melanogaster Fpps 36209   NP_477380 47
S.cerevisiae ERG20 853272   NP_012368 46
A.gambiae AgaP_AGAP007104 1269998   XP_308653 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)