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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HDAC2, histone deacetylase 2
Sequence ID:NM_001527
NR_033441
NR_073443
Entrez Gene ID:3066
Ensembl ID:ENSG00000196591

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 114261881 - 114291888

 Exon Info From UCSC:
NM_001527

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100015853Full LengthBC148797histone deacetylase 2
5271899IncompleteBC031055histone deacetylase 2
100015085BC146376histone deacetylase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001518  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001527 NP_001518 Q92769 EC 3.5.1.98 Hist_deacetyl

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U31814 AAC50814 Q92769 EC 3.5.1.98
BC031055 AAH31055 Q92769 EC 3.5.1.98
BC146376 AAI46377    
BC148797 AAI48798    
AB209190 BAD92427 Q59GB9  
AK092156 BAG52487 B3KRS5  
AK097376 BAG53457 B3KUJ5  
AK296856 BAG59420 Q92769 EC 3.5.1.98

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HDAC2 NP_001518 M.musculus Hdac2 15182 Gene Info NP_032255 100
R.norvegicus Hdac2 84577   NP_445899 99
C.elegans hda-3 173074   NP_493026 63
A.thaliana HDA6 836431   NP_201116 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta