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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ARHGEF5, Rho guanine nucleotide exchange factor (GEF) 5
Sequence ID:NM_005435
NM_001002861
Entrez Gene ID:7984
Ensembl ID:ENSG00000050327

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:7q35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 144062001 - 144077724


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020651Full LengthBC136661Rho guanine nucleotide exchange factor (GEF) 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005426  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005435 NP_005426 Q12774 SH3_1
PH
RhoGEF
SH3_2

Related Sequences

 
mRNAGenPeptSwissProt
U02082 AAA18010 Q12774
BC010046 AAH10046 Q12774
BC011839 AAH11839 Q12774
BC014555 AAH14555 Q12774
BC136661 AAI36662 B9EGR7
DQ893512 ABM84438  
DQ896485 ABM87484  
AK160365 BAD18708 Q12774
AK090570 BAG52188 B3KQX6
CR749203 CAH18061 Q68E09

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ARHGEF5 NP_005426 M.musculus Arhgef5 54324 Gene Info NP_598435 67
R.norvegicus Arhgef5 140898   XP_342677 66

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta