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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. CYP2D6, cytochrome P450, family 2, subfamily D, polypeptide 6
Sequence ID:NM_000106
NM_001025161
RefSeqGene ID:NG_008376
Entrez Gene ID:1565
Ensembl ID:ENSG00000100197

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CODEINE SENSITIVITY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 42537251 - 42540550

 Exon Info From UCSC:
NM_000106
NM_001025161

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7002157Full LengthBC067432cytochrome P450, family 2, subfamily D, polypeptide 6
30915411Full LengthBC075023cytochrome P450, family 2, subfamily D, polypeptide 6
30915622Full LengthBC075024cytochrome P450, family 2, subfamily D, polypeptide 6
40024713Full LengthBC106757cytochrome P450, family 2, subfamily D, polypeptide 6
40024717Full LengthBC106758cytochrome P450, family 2, subfamily D, polypeptide 6
40024719Full LengthBC126858cytochrome P450, family 2, subfamily D, polypeptide 6
7002156IncompleteBC066877cytochrome P450, family 2, subfamily D, polypeptide 6

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000106 NP_000097 Q6NWU0
P10635
EC 1.14.14.1 p450
NM_001025161 NP_001020332     p450

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M24499 AAA36403 Q16804  
M20403 AAA52153 P10635 EC 1.14.14.1
BC066877 AAH66877 P10635 EC 1.14.14.1
BC067432 AAH67432 Q6NWU0  
BC075023 AAH75023 P10635 EC 1.14.14.1
BC075024 AAH75024 P10635 EC 1.14.14.1
BC106757 AAI06758 Q6ICD8  
BC106758 AAI06759 Q3KPF3  
BC126858 AAI26859 Q6NWU0  
AY220845 AAO49806 Q6XP50  
AY663390 AAU87043 Q5Y7H2  
AB209492 BAD92729 Q59FG8  
X08006 CAA30807 P10635 EC 1.14.14.1
CR456430 CAG30316 Q6ICD8  
CU013213 CAK54644    
CU013501 CAK54943    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP2D6 NP_000097 R.norvegicus Cyp2d3 24303   NP_775116 72
M.musculus Cyp2d10 13101 Gene Info NP_034135 71
M.musculus Cyp2d9 13105 Gene Info NP_034136 71
M.musculus Cyp2d34 223706 Gene Info NP_663449 70
M.musculus Cyp2d11 545123 Gene Info NP_001098001 69
M.musculus Cyp2d12 380997 Gene Info NP_958748 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)