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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. OPTN, optineurin
Sequence ID:NM_001008211
NM_001008212
NM_001008213
NM_021980
RefSeqGene ID:NG_012876
Entrez Gene ID:10133
Ensembl ID:ENSG00000123240

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AMYOTROPHIC LATERAL SCLEROSIS 12 
GLAUCOMA 1, OPEN ANGLE, ECYP1B1
WDR36
GLAUCOMA, NORMAL TENSIONOPA1

Cytogenetic Location (from UniGene)

Cytogenetic Location:10p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 13168028 - 13178798

 Exon Info From UCSC:
NM_001008211
NM_001008212
NM_001008213
NM_021980

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3457195Full LengthBC032762optineurin
3831267Full LengthBC013876optineurin

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001008211 NP_001008212 Q96CV9  
NM_001008212 NP_001008213 Q96CV9  
NM_001008213 NP_001008214 Q96CV9  
NM_021980 NP_068815 Q96CV9  

Related Sequences

 
mRNAGenPeptSwissProt
AF061034 AAC16046 Q96CV9
AF061034 AAC16047 Q96CV9
AF049614 AAC26850 Q96CV9
BC013876 AAH13876 Q96CV9
BC032762 AAH32762 Q96CV9
AF420371 AAL76327 Q96CV9
AF420372 AAL76328 Q96CV9
AF420373 AAL76329 Q96CV9
DQ893651 ABM84577  
DQ895820 ABM86746  
AK055403 BAG51512 Q96CV9
AK303715 BAG64696 B4E184
AK316171 BAH14542 B7ZA56

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens OPTN NP_001008212 M.musculus Optn 71648 Gene Info NP_862896 80
R.norvegicus Optn 246294   NP_659549 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)