Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SPPL2B, signal peptide peptidase like 2B
Sequence ID:NM_001077238
RefSeqGene ID:NG_032984
Entrez Gene ID:56928

Database Links

UniGeneEntrez GeneOMIMHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 2328679 - 2354799

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3352341Full LengthBC001788signal peptide peptidase-like 2B
4822524Full LengthBC028391signal peptide peptidase-like 2B
30395602Full LengthBC093046signal peptide peptidase-like 2B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_694533  

Protein Infomation

NM_001077238 NP_001070706    
NM_152988 NP_694533 Q8TCT7 PA

Related Sequences

BC001788 AAH01788 Q8TCT7
BC028391 AAH28391 Q8TCT7
BC093046 AAH93046 Q8TCT7
AY169315 AAO12540 Q8TCT7
AB040965 BAA96056 Q8TCT7
AL365405 CAB96951 Q8TCT7
AJ345027 CAC87788 Q8TCT7
AJ420897 CAD13134 Q8TCT7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SPPL2B NP_694533 M.musculus 3110056O03Rik 73218 Gene Info NP_780404 80
R.norvegicus Sppl2b 362828   NP_001014222 80
A.thaliana SPPL3 818909   NP_850383 37
A.thaliana SPPL5 837092   NP_172073 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)