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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CHRNB1, cholinergic receptor, nicotinic, beta 1 (muscle)
Sequence ID:NM_000747
RefSeqGene ID:NG_008026
Entrez Gene ID:1140
Ensembl ID:ENSG00000170175

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH ACETYLCHOLINE RECEPTOR DEFICIENCYCHRNE
MUSK
RAPSN
MYASTHENIC SYNDROME, SLOW-CHANNEL CONGENITALCHRNA1
CHRND
CHRNE

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 7348840 - 7360245

 Exon Info From UCSC:
NM_000747

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3531876Full LengthBC023553cholinergic receptor, nicotinic, beta 1 (muscle)
3874415Full LengthBC011371cholinergic receptor, nicotinic, beta 1 (muscle)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000738  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000747 NP_000738 P11230 Neur_chan_LBD
Neur_chan_memb

Related Sequences

 
mRNAGenPeptSwissProt
BC011371 AAH11371 P11230
BC023553 AAH23553 Q8IZ46
DQ894641 ABM85567  
AK294880 BAH11912 B7Z2M6
AK298938 BAH12907 B7Z5H1
X14830 CAA32939 P11230

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CHRNB1 NP_000738 M.musculus Chrnb1 11443 Gene Info NP_033731 90
R.norvegicus Chrnb1 24261   NP_036660 89

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta