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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GRK4, G protein-coupled receptor kinase 4
Sequence ID:NM_182982
NM_001004056
NM_001004057
RefSeqGene ID:NG_029102
Entrez Gene ID:2868
Ensembl ID:ENSG00000125388

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4p16.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 2966672 - 2968323

 Exon Info From UCSC:
NM_182982
NM_001004056
NM_001004057

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40125871Full LengthBC117320G protein-coupled receptor kinase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_892027  NP_001004056  NP_001004057  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001004056 NP_001004056     Pkinase
RGS
Pkinase_Tyr
NM_001004057 NP_001004057     Pkinase
RGS
Pkinase_Tyr
NM_182982 NP_892027 P32298 EC 2.7.11.16 Pkinase
RGS
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U33054 AAC50406 P32298 EC 2.7.11.16
U33055 AAC50407 P32298 EC 2.7.11.16
U33056 AAC50408 P32298 EC 2.7.11.16
BC117320 AAI17321 P32298 EC 2.7.11.16
HQ258463 ADR83217    
AK223581 BAD97301 P32298 EC 2.7.11.16
AK292390 BAF85079 A8K8M5  
X75897 CAA53506 P32298 EC 2.7.11.16
X97879 CAA66468 P32298 EC 2.7.11.16
X97880 CAA66469 P32298 EC 2.7.11.16
X97881 CAA66470 P32298 EC 2.7.11.16
X98118 CAA66802 P32298 EC 2.7.11.16

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GRK4 NP_892027 R.norvegicus Grk4 59077   NP_075217 76
M.musculus Grk4 14772 Gene Info NP_062370 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta