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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TNKS2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Sequence ID:NM_025235
Entrez Gene ID:80351
Ensembl ID:ENSG00000107854

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 93558447 - 93625032

 Exon Info From UCSC:
NM_025235

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100063626Full LengthBC156931tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
100015528BC148498tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_079511  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_025235 NP_079511 Q9H2K2 EC 2.4.2.30 Ank
PARP
SAM_2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF305081 AAG25674 Q9H2K2 EC 2.4.2.30
AF264912 AAG44694 Q9H2K2 EC 2.4.2.30
BC148498 AAI48499    
BC156931 AAI56932    
AF329696 AAK13463 Q9H2K2 EC 2.4.2.30
AF342982 AAK25811 Q9H2K2 EC 2.4.2.30
AF309033 AAK82330 Q9H2K2 EC 2.4.2.30
AF438201 AAL40795 Q9H2K2 EC 2.4.2.30
AK023746 BAB14665 Q9H2K2 EC 2.4.2.30
AK314612 BAG37180 Q9H2K2 EC 2.4.2.30

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TNKS2 NP_079511 M.musculus Tnks2 74493 Gene Info NP_001157107 97
R.norvegicus Tnks2 309512   NP_001101077 97
A.gambiae AgaP_AGAP001947 1281178   XP_321116 69
D.melanogaster tankyrase 43095   NP_651410 67

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)