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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. VKORC1, vitamin K epoxide reductase complex, subunit 1
Sequence ID:NM_024006
NM_206824
RefSeqGene ID:NG_011564
Entrez Gene ID:79001
Ensembl ID:ENSG00000167397

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
COUMARIN RESISTANCECYP2A6
CYP2C9
F9
VITAMIN K-DEPENDENT CLOTTING FACTORS, COMBINED DEFICIENCY OF, 2 

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 31102174 - 31106261

 Exon Info From UCSC:
NM_024006
NM_206824

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3944530Full LengthBC002911vitamin K epoxide reductase complex, subunit 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_076869  NP_996560  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_024006 NP_076869 Q9BQB6 EC 1.1.4.1 VKOR
NM_206824 NP_996560     VKOR

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC002911 AAH02911 Q9BQB6 EC 1.1.4.1
AF176924 AAQ13668 Q9BQB6 EC 1.1.4.1
AY466113 AAR28759 Q9BQB6 EC 1.1.4.1
AY423044 AAR82914 Q9BQB6 EC 1.1.4.1
AY521634 AAS01052 Q9BQB6 EC 1.1.4.1
JF432549 ADZ15766    
AK125618 BAC86222 Q6ZUK0  
AK289790 BAF82479 Q9BQB6 EC 1.1.4.1
AK312005 BAG34943 Q9BQB6 EC 1.1.4.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens VKORC1 NP_076869 M.musculus Vkorc1 27973 Gene Info NP_848715 86
R.norvegicus Vkorc1 309004   NP_976080 84
D.melanogaster Vkor 3346188   NP_001014533 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)