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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. REN, renin
Sequence ID:NM_000537
RefSeqGene ID:NG_012122
Entrez Gene ID:5972
Ensembl ID:ENSG00000143839

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPERURICEMIC NEPHROPATHY, FAMILIAL JUVENILE 2 
RENAL TUBULAR DYSGENESISACE
AGT
AGTR1
AGTR1

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 204131141 - 204141702

NM_000537 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
29390204123943204124304
391489204124947204125045
490631204125305204125446
632751204125804204125923
752760204126488204126496
761957204128526204128722
9581076204129687204129805
10771200204130419204130542
12011351204131140204131290
13521493204135323204135464

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5188566Full LengthBC033474renin
5590211Full LengthBC047752renin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000528  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000537 NP_000528 P00797 EC 3.4.23.15 Asp
A1_Propeptide

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF117822 AAD26254 Q9UQK5  
BC033474 AAH33474 P00797 EC 3.4.23.15
BC047752 AAH47752 P00797 EC 3.4.23.15
HQ448652 ADQ33130    
X00063 CAA24937 Q15296  
CR536498 CAG38737 P00797 EC 3.4.23.15

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens REN NP_000528 M.musculus Ren1 19701 Gene Info NP_112469 71
R.norvegicus Ren 24715   NP_036774 67
D.melanogaster CG10104 36602   NP_610961 41
P.falciparum PF14_0076 811658   XP_001348249 37
P.falciparum PF14_0077 811659   XP_001348250 35
P.falciparum PF14_0075 811657   XP_001348248 35
P.falciparum PF14_0078 811660   XP_001348251 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta