Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FLCN, folliculin
Sequence ID:NM_144606
NM_144997
RefSeqGene ID:NG_008001
Entrez Gene ID:201163
Ensembl ID:ENSG00000154803

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BIRT-HOGG-DUBE SYNDROME 
COLON CANCERAKT1
APC
APC
AURKA
AXIN2
BCL10
BUB1B
CCND1
EP300
FGFR3
MLH3
NRAS
ODC1
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
SMAD7
TLR2
TLR4
TP53
TP53
PNEUMOTHORAX, PRIMARYSPONTANEOUS 
RENAL CARCINOMA, CHROMOPHOBE, SOMATICDIRC2
HNF1A
HNF1B
OGG1
RNF139
VHL

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 17115526 - 17140453

 Exon Info From UCSC:
NM_144606
NM_144997

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4684974Full LengthBC015687folliculin
3922049IncompleteBC015725folliculin

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_144606 NP_653207    
NM_144997 NP_659434 Q8NFG4  

Related Sequences

 
mRNAGenPeptSwissProt
BC015687 AAH15687 Q8NFG4
BC015725 AAH15725 Q8NFG4
AF517523 AAM94803 Q8NFG4
HQ447198 ADQ31685  
AK126951 BAC86760 Q8NFG4
AK127912 BAC87186 Q8NFG4
AL831885 CAD38565 Q8NDS2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FLCN NP_659434 M.musculus Flcn 216805 Gene Info NP_666130 93
R.norvegicus Flcn 303185   NP_955422 93
A.gambiae AgaP_AGAP007579 1269650   XP_308295 35
D.melanogaster BHD 38793   NP_648090 33
C.elegans F22D3.2 174134   NP_001022107 29

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)