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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. AQP4, aquaporin 4
Sequence ID:NM_001650
RefSeqGene ID:NG_029560
Entrez Gene ID:361
Ensembl ID:ENSG00000171885

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:18q11.2-q12.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:18: 24436174 - 24445653

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4717755Full LengthBC022286aquaporin 4
4792064IncompleteBC045780aquaporin 4
4794191IncompleteBC030745aquaporin 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004019  NP_001641  

Protein Infomation

NM_001650 NP_001641 P55087 MIP
NM_004028 NP_004019   MIP

Related Sequences

U63622 AAB26957 P55087
U63623 AAB26958 P55087
U34845 AAC50284 P55087
BC022286 AAH22286 P55087
HQ447648 ADQ32133  
HQ901095 ADZ13511 F1DSG4
D63412 BAA09715 P55087
AB128929 BAD22823 Q6L7A0
AB209156 BAD92393 Q59GF3
AK222684 BAD96404 Q53H97
AK295069 BAG58116 B4DHF5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens AQP4 NP_001641 R.norvegicus Aqp4 25293   NP_036957 94
M.musculus Aqp4 11829 Gene Info NP_033830 93
A.gambiae AQP_ANOGA 1279812   XP_319584 53
D.melanogaster Drip 36236   NP_523697 46
A.thaliana PIP2;8 816186   NP_179277 44
A.thaliana PIP3 829662   NP_001190920 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)