Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. AARS, alanyl-tRNA synthetase
Sequence ID:NM_001605
RefSeqGene ID:NG_023191
Entrez Gene ID:16
Ensembl ID:ENSG00000090861

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 70286287 - 70323409

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3450606Full LengthBC011451alanyl-tRNA synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001596  

Protein Infomation

NM_001605 NP_001596 P49588 EC tRNA-synt_2c

Related Sequences

BC011451 AAH11451 P49588 EC
DQ891634 ABM82560    
DQ894824 ABM85750    
D32050 BAA06808 P49588 EC
AK222824 BAD96544 P49588 EC
AK299098 BAG61157 B4DR45  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens AARS NP_001596 M.musculus Aars 234734 Gene Info NP_666329 96
R.norvegicus Aars 292023   NP_001093987 95
A.gambiae AgaP_AGAP009701 1279087   XP_318757 61
D.melanogaster Aats-ala 34156   NP_523511 61
C.elegans ars-2 171985   NP_491281 59
S.cerevisiae ALA1 854513   NP_014980 52
A.thaliana ALATS 841442   NP_001185186 51
S.pombe ala1 2542031   NP_593640 50
N.crassa NCU02566 3881815   XP_965697 48
P.falciparum PF13_0354 814313   XP_001350388 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)