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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. POLD2, polymerase (DNA directed), delta 2, accessory subunit
Sequence ID:NM_001127218
NM_001256879
NM_006230
Entrez Gene ID:5425
Ensembl ID:ENSG00000106628

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 44154293 - 44163107

 Exon Info From UCSC:
NM_001127218
NM_006230

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822169Full LengthBC000459polymerase (DNA directed), delta 2, regulatory subunit 50kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006221  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001127218 NP_001120690 P49005 EC 2.7.7.7  
NM_001256879 NP_001243808      
NM_006230 NP_006221 P49005 EC 2.7.7.7 DNA_pol_E_B

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U21090 AAC50216 P49005 EC 2.7.7.7
BC000459 AAH00459 P49005 EC 2.7.7.7
DQ891999 ABM82925    
DQ895189 ABM86115    
AK292347 BAF85036 A4D2J4  
AK312294 BAG35221 B2R5S4  
AK298168 BAG60440 B4DP28  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens POLD2 NP_001120690 R.norvegicus Pold2 289758   NP_001013068 94
M.musculus Pold2 18972 Gene Info NP_032920 94
A.thaliana POLD2 818812   NP_973664 45
A.gambiae AgaP_AGAP008910 1279877   XP_319657 45
D.melanogaster CG12018 38228   NP_647659 44
N.crassa NCU03763 3877275   XP_961110 38
S.pombe cdc1 2542083   NP_594406 37
S.cerevisiae POL31 853462   NP_012539 34

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)