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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MERTK, c-mer proto-oncogene tyrosine kinase
Sequence ID:NM_006343
RefSeqGene ID:NG_011607
Entrez Gene ID:10461
Ensembl ID:ENSG00000153208

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
RETINITIS PIGMENTOSA 38 
RETINITIS PIGMENTOSA,JUVENILE, AUTOSOMAL RECESSIVEC2orf71
CNGB1
CRX
CRX
CRX
RLBP1
SPATA7
USH2A

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q14.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 112751964 - 112786921

 Exon Info From UCSC:
NM_006343

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40012335Full LengthBC114918c-mer proto-oncogene tyrosine kinase
40068588Full LengthBC114917c-mer proto-oncogene tyrosine kinase

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006343 NP_006334 Q12866 EC 2.7.10.1  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U08023 AAB60430 Q12866 EC 2.7.10.1
BC114917 AAI14918 Q1RMG3  
BC114918 AAI14919 Q1RMG3  
D16316 BAA03823 Q07941  
AK316584 BAG38172 B2RE75  
AK294196 BAG57511 B4DFQ0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MERTK NP_006334 M.musculus Mertk 17289 Gene Info NP_032613 82
R.norvegicus Mertk 65037   NP_075232 81

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)