Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. DSTN, destrin (actin depolymerizing factor)
Sequence ID:NM_001011546
Entrez Gene ID:11034
Ensembl ID:ENSG00000125868

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:20p12.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 17550835 - 17588120

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3938287Full LengthBC009477destrin (actin depolymerizing factor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006861  NP_001011546  

Protein Infomation

NM_001011546 NP_001011546   Cofilin_ADF
NM_006870 NP_006861 P60981 Cofilin_ADF

Related Sequences

S65738 AAB28361 P60981
BC009477 AAH09477 P60981
JF432564 ADZ15781  
AK312645 BAG35529 P60981
AK302338 BAG63668 P60981
AK315994 BAH14365 B7Z9M9
CR457042 CAG33323 P60981
CR541956 CAG46754 P60981

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens DSTN NP_006861 M.musculus Dstn 56431 Gene Info NP_062745 96
R.norvegicus Dstn 502674   NP_001028838 96
R.norvegicus Dstnl1 296197   XP_215862 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)