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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TTC8, tetratricopeptide repeat domain 8
Sequence ID:NM_144596
NM_198309
NM_198310
RefSeqGene ID:NG_008126
Entrez Gene ID:123016
Ensembl ID:ENSG00000165533

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BARDET-BIEDL SYNDROME 1ARL6
BBS1
BBS10
BBS12
BBS2
BBS4
BBS5
BBS7
BBS9
CCDC28B
CEP290
MKKS
MKS1
TMEM67
TRIM32
WDPCP

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q31.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 89341431 - 89344329

 Exon Info From UCSC:
NM_144596
NM_198309
NM_198310

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4799330Full LengthBC026351tetratricopeptide repeat domain 8
30368216Full LengthBC095433tetratricopeptide repeat domain 8
3453572IncompleteBC001563tetratricopeptide repeat domain 8

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_938051  NP_938052  NP_653197  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_144596 NP_653197   TPR_1
TPR_2
NM_198309 NP_938051   TPR_1
TPR_2
NM_198310 NP_938052   TPR_1
TPR_2

Related Sequences

 
mRNAGenPeptSwissProt
BC001563 AAH01563 Q8TAM2
BC026351 AAH26351 Q8TAM2
BC095433 AAH95433 Q8TAM2
AY366523 AAR02192 Q8TAM2
AY366524 AAR02193 Q8TAM2
AY373972 AAR19043 Q8TAM2
AK093891 BAG52780 B3KSL8
AK124675 BAG54067 Q8TAM2
AK296077 BAG58833 B4DJH1
AL833901 CAD38757 Q8TAM2
BX161472 CAD61928 Q8TAM2
BX247959 CAD62299 Q86U25
BX248071 CAD62360 Q8TAM2
BX248248 CAD62576 Q8TAM2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TTC8 NP_653197 M.musculus Ttc8 76260 Gene Info NP_938053 95
R.norvegicus Ttc8 299246   NP_001100222 92
C.elegans bbs-8 188904   NP_504711 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)