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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SPR, sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Sequence ID:NM_003124
RefSeqGene ID:NG_008234
Entrez Gene ID:6697
Ensembl ID:ENSG00000116096

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:2p14-p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 73114523 - 73119286

NM_003124 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
13547311451173114864
3556457311544273115732
64614597311847573119288

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5089862Full LengthBC017310sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003115  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003124 NP_003115 P35270 EC 1.1.1.153 adh_short

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M76231 AAA60314 P35270 EC 1.1.1.153
S71376 AAD14079 Q93041  
BC017310 AAH17310 P35270 EC 1.1.1.153
DQ891699 ABM82625    
DQ894880 ABM85806    
AK222942 BAD96662 P35270 EC 1.1.1.153
AK291856 BAF84545 P35270 EC 1.1.1.153

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SPR NP_003115 M.musculus Spr 20751 Gene Info NP_035597 75
R.norvegicus Spr 29270   NP_062054 75
A.gambiae AgaP_AGAP008000 1277951   XP_317468 39
D.melanogaster Sptr 31781   NP_727265 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)