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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SPR, Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Sequence ID:NM_003124
RefSeqGene ID:NG_008234
Entrez Gene ID:6697
Ensembl ID:ENSG00000116096

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p14-p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 73114523 - 73119286

NM_003124 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5089862Full LengthBC017310sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003115  

Protein Infomation

NM_003124 NP_003115 P35270 EC adh_short

Related Sequences

M76231 AAA60314 P35270 EC
S71376 AAD14079 Q93041  
BC017310 AAH17310 P35270 EC
DQ891699 ABM82625    
DQ894880 ABM85806    
AK222942 BAD96662 P35270 EC
AK291856 BAF84545 P35270 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SPR NP_003115 M.musculus Spr 20751 Gene Info NP_035597 75
R.norvegicus Spr 29270   NP_062054 75
A.gambiae AgaP_AGAP008000 1277951   XP_317468 39
D.melanogaster Sptr 31781   NP_727265 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)