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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CD3E, CD3e molecule, epsilon (CD3-TCR complex)
Sequence ID:NM_000733
RefSeqGene ID:NG_007383
Entrez Gene ID:916
Ensembl ID:ENSG00000198851

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
SEVERE COMBINED IMMUNODEFICIENCY, T CELL-NEGATIVE, B-CELL/NATURALKILLER-CELL POSITIVECD3D
IL7R
PTPRC

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 118182858 - 118185506

NM_000733 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1197118175294118175490
198305118175608118175715
306326118178002118178022
327341118179141118179155
342359118182867118182884
360608118183332118183580
609776118184421118184588
777823118185162118185208
8241512118186200118186888

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5214563Full LengthBC049847CD3e molecule, epsilon (CD3-TCR complex)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000724  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000733 NP_000724 P07766 ITAM

Related Sequences

 
mRNAGenPeptSwissProt
BC049847 AAH49847 P07766
AK292612 BAF85301 P07766
AK301255 BAG62822 B4DVW0
X03884 CAA27516 P07766

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CD3E NP_000724 R.norvegicus Cd3e 315609   NP_001101610 68
M.musculus Cd3e 12501 Gene Info NP_031674 64

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta