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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DEGS1, Delta(4)-desaturase, sphingolipid 1
Sequence ID:NM_003676
Entrez Gene ID:8560
Ensembl ID:ENSG00000143753

Database Links

UniGeneEntrez GeneEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q42.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 224370958 - 224380859

NM_003676 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1193224370927224371119
194936224377278224378020
9372043224380033224381139

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3450936Full LengthBC000961degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003667  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003676 NP_003667 O15121 FA_desaturase
Lipid_DES

Related Sequences

 
mRNAGenPeptSwissProt
AF002668 AAB62238 O15121
BC000961 AAH00961 O15121
AF466375 AAM12531 O15121
AY423730 AAS00493 O15121
HQ447864 ADQ32348  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DEGS1 NP_003667 M.musculus Degs1 13244 Gene Info NP_031879 85
R.norvegicus Degs1 58970   NP_445775 85
C.elegans F33D4.4 177548   NP_501256 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)