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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FBL, Fibrillarin
Sequence ID:NM_001436
Entrez Gene ID:2091
Ensembl ID:ENSG00000105202

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 40325180 - 40331430

NM_001436 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
81164032509340325201
1172624032530740325452
2633754032719540327307
3765084032835040328482
5096794032967440329844
6807744033087240330966
7758764033105340331154
87710474033125640331426
104811714033693040337053

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3504198Full LengthBC019260fibrillarin
3856436IncompleteBC015218fibrillarin
4538098IncompleteBC019609fibrillarin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001427  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001436 NP_001427 P22087 Fibrillarin

Related Sequences

 
mRNAGenPeptSwissProt
M59849 AAA52453 P22087
BC015218 AAH15218 Q96BS4
BC019260 AAH19260 P22087
BC019609 AAH19609 Q96BS4
BT006830 AAP35476 P22087
BT020144 AAV38946 P22087
DQ892314 ABM83240  
DQ895517 ABM86443  
AK296950 BAG59496 B4DLD4
AB451384 BAG70198 P22087
X56597 CAA39935 P22087
CR457069 CAG33350 P22087

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FBL NP_001427 M.musculus Fbl 14113 Gene Info NP_032017 98
R.norvegicus Fbl 292747   NP_001020814 97
A.gambiae AgaP_AGAP011244 1270682   XP_309401 81
D.melanogaster Fib 37662   NP_523817 81
A.thaliana FIB1 835323   NP_568772 77
A.thaliana FIB2 828668   NP_567724 73
C.elegans fib-1 179999   NP_506691 73
S.pombe fib1 2540479   NP_596229 73
S.cerevisiae NOP1 851548   NP_010270 70
N.crassa NCU03702 3877642   XP_961478 70
P.falciparum PF14_0068 811650   XP_001348241 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta