Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DUSP6, dual specificity phosphatase 6
Sequence ID:NM_001946
NM_022652
Entrez Gene ID:1848
Ensembl ID:ENSG00000139318

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q22-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 89742143 - 89746168

 Exon Info From UCSC:
NM_001946
NM_022652

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2906126Full LengthBC003143dual specificity phosphatase 6
3547162Full LengthBC003562dual specificity phosphatase 6
3954486Full LengthBC005047dual specificity phosphatase 6
5183133Full LengthBC037236dual specificity phosphatase 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_073143  NP_001937  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001946 NP_001937 Q16828 EC 3.1.3.16
EC 3.1.3.48
Rhodanese
DSPc
NM_022652 NP_073143     Rhodanese
DSPc

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC003143 AAH03143 Q16828 EC 3.1.3.16
EC 3.1.3.48
BC003562 AAH03562 Q16828 EC 3.1.3.16
EC 3.1.3.48
BC005047 AAH05047 Q16828 EC 3.1.3.16
EC 3.1.3.48
BC037236 AAH37236 Q16828 EC 3.1.3.16
EC 3.1.3.48
BT006895 AAP35541 Q16828 EC 3.1.3.16
EC 3.1.3.48
DQ892490 ABM83416    
DQ895701 ABM86627    
AB013602 BAA31969 Q16828
Q53GP9
EC 3.1.3.16
EC 3.1.3.48
AB013382 BAA34369 Q16828 EC 3.1.3.16
EC 3.1.3.48
AB189400 BAD38886 Q689E8  
AK222882 BAD96602 Q53GP9  
AB451265 BAG70079 B5BU29  
AB451393 BAG70207 B5BU29  
X93920 CAA63813 Q16828 EC 3.1.3.16
EC 3.1.3.48

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DUSP6 NP_001937 R.norvegicus Dusp6 116663   NP_446335 99
M.musculus Dusp6 67603 Gene Info NP_080544 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta