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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ACE, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Sequence ID:NM_000789
NM_001178057
NM_152830
NM_152831
RefSeqGene ID:NG_011648
Entrez Gene ID:1636
Ensembl ID:ENSG00000159640

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ALZHEIMER DISEASEA2M
APBB2
APP
BLMH
HFE
MPO
NOS3
PAXIP1
PLAU
SORL1
MICROVASCULAR COMPLICATIONS OF DIABETES 1VEGFA
MICROVASCULAR COMPLICATIONS OF DIABETES 3 
RENAL TUBULAR DYSGENESISAGT
AGTR1
AGTR1
REN
STROKE, HEMORRHAGICCOL4A2

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 61554431 - 61574524

 Exon Info From UCSC:
NM_000789
NM_001178057
NM_152830

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4826875Full LengthBC036375angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_690043  NP_000780  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000789 NP_000780 P12821 EC 3.4.15.1 Peptidase_M2
NM_001178057 NP_001171528      
NM_152830 NP_690043     Peptidase_M2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J04144 AAA51684 P12821 EC 3.4.15.1
M26657 AAA60611 P12821 EC 3.4.15.1
S81361 AAD14360 Q16425  
JQ927553 AFK65504 I3UJJ7  
AB208971 BAD92208 P12821 EC 3.4.15.1
AK296566 BAG59186 B4DKH4  
AK300516 BAG62228 B4DU66  
AK301988 BAG63395 P12821 EC 3.4.15.1
AK302019 BAG63418 B4DXK6  
X16295 CAA34362 P12821 EC 3.4.15.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ACE NP_000780 R.norvegicus Ace 24310   NP_036676 85
M.musculus Ace 11421 Gene Info NP_997507 83
A.gambiae ANCE9 1274704   XP_313865 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta