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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MMP13, Matrix metallopeptidase 13 (collagenase 3)
Sequence ID:NM_002427
RefSeqGene ID:NG_021404
Entrez Gene ID:4322
Ensembl ID:ENSG00000137745

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
METAPHYSEAL ANADYSPLASIA 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 102814521 - 102826463

NM_002427 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
191391102813722102815094
13921495102816374102816477
14961655102818619102818778
16561789102819753102819886
17901907102820838102820955
19082069102822740102822901
20702195102824884102825009
21962344102825186102825334
23452586102825980102826221
25872735102826314102826462

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7002184Full LengthBC067522matrix metallopeptidase 13 (collagenase 3)
7002185Full LengthBC067523matrix metallopeptidase 13 (collagenase 3)
30915315Full LengthBC074807matrix metallopeptidase 13 (collagenase 3)
30915529Full LengthBC074808matrix metallopeptidase 13 (collagenase 3)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002418  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002427 NP_002418 P45452 Hemopexin
Peptidase_M10
PG_binding_1

Related Sequences

 
mRNAGenPeptSwissProt
BC067522 AAH67522 P45452
BC067523 AAH67523 Q6NWN6
BC074807 AAH74807 P45452
BC074808 AAH74808 P45452
AY256443 AAP78939 Q7Z5M1
AY256444 AAP78940 Q7Z5M0
HQ258010 ADR82764  
AK222748 BAD96468 Q53H33
AK292211 BAF84900 A8K846
AK315341 BAG37740 B2RCZ3
X75308 CAA53056 P45452
X81334 CAA57108 P45452

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MMP13 NP_002418 M.musculus Mmp13 17386 Gene Info NP_032633 87
R.norvegicus Mmp13 171052   NP_598214 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)