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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MAP3K3, mitogen-activated protein kinase kinase kinase 3
Sequence ID:NM_002401
Entrez Gene ID:4215
Ensembl ID:ENSG00000198909

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 61769614 - 61772451

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6183752Full LengthBC090859mitogen-activated protein kinase kinase kinase 3
7939517Full LengthBC093672mitogen-activated protein kinase kinase kinase 3
7939519Full LengthBC093674mitogen-activated protein kinase kinase kinase 3
3506235IncompleteBC008336mitogen-activated protein kinase kinase kinase 3
4179950IncompleteBC010464mitogen-activated protein kinase kinase kinase 3
4286869IncompleteBC018021mitogen-activated protein kinase kinase kinase 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_976226  NP_002392  

Protein Infomation

NM_002401 NP_002392 Q99759 EC Pkinase
NM_203351 NP_976226     Pkinase

Related Sequences

U78876 AAB41729 Q99759 EC
BC008336 AAH08336 Q96HN9  
BC090859 AAH90859 Q99759 EC
BC093672 AAH93672 Q99759 EC
BC093674 AAH93674 Q99759 EC
AF172823 AAQ13617 Q7Z4E6  
DQ454151 ABE11554 Q1PBM3  
AK315305 BAG37709 Q99759 EC
AL834303 CAD38973 Q99759 EC
AX775739 CAE11569    
AX775741 CAE11570    
AM392833 CAL37711    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MAP3K3 NP_976226 M.musculus Map3k3 26406 Gene Info NP_036077 97
R.norvegicus Map3k3 303604   NP_001100528 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta