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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP3K3, Mitogen-activated protein kinase kinase kinase 3
Sequence ID:NM_203351
NM_002401
Entrez Gene ID:4215
Ensembl ID:ENSG00000198909

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:17q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 61769614 - 61772451

 Exon Info From UCSC:
NM_203351
NM_002401

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6183752Full LengthBC090859mitogen-activated protein kinase kinase kinase 3
7939517Full LengthBC093672mitogen-activated protein kinase kinase kinase 3
7939519Full LengthBC093674mitogen-activated protein kinase kinase kinase 3
3506235IncompleteBC008336mitogen-activated protein kinase kinase kinase 3
4179950IncompleteBC010464mitogen-activated protein kinase kinase kinase 3
4286869IncompleteBC018021mitogen-activated protein kinase kinase kinase 3
9051725IncompleteBC143224 

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_976226  NP_002392  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002401 NP_002392 Q99759 EC 2.7.11.25 Pkinase
PB1
NM_203351 NP_976226     Pkinase
PB1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U78876 AAB41729 Q99759 EC 2.7.11.25
BC008336 AAH08336 Q96HN9  
BC090859 AAH90859 Q99759 EC 2.7.11.25
BC093672 AAH93672 Q99759 EC 2.7.11.25
BC093674 AAH93674 Q99759 EC 2.7.11.25
AF172823 AAQ13617 Q7Z4E6  
DQ454151 ABE11554 Q1PBM3  
AK315305 BAG37709 Q99759 EC 2.7.11.25
AL834303 CAD38973 Q99759 EC 2.7.11.25
AX775739 CAE11569    
AX775741 CAE11570    
AM392833 CAL37711    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP3K3 NP_976226 M.musculus Map3k3 26406 Gene Info NP_036077 97
R.norvegicus Map3k3 303604   NP_001100528 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta