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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. XRCC6, X-ray repair complementing defective repair in Chinese hamster cells 6
Sequence ID:NM_001469
Entrez Gene ID:2547
Ensembl ID:ENSG00000196419

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 42033339 - 42034782

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3448510Full LengthBC018259X-ray repair complementing defective repair in Chinese hamster cells 6
3509801Full LengthBC008343X-ray repair complementing defective repair in Chinese hamster cells 6
3536083Full LengthBC010034X-ray repair complementing defective repair in Chinese hamster cells 6
4561541Full LengthBC012154X-ray repair complementing defective repair in Chinese hamster cells 6
6167735Full LengthBC072449X-ray repair complementing defective repair in Chinese hamster cells 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001460  

Protein Infomation

NM_001469 NP_001460 P12956 SAP

Related Sequences

M32865 AAA36155 P12956
J04611 AAA51733 P12956
J04607 AAA61177 P12956
S38729 AAB22381 P12956
BC008343 AAH08343 P12956
BC010034 AAH10034 P12956
BC012154 AAH12154 P12956
BC018259 AAH18259 P12956
BC072449 AAH72449 P12956
EU446892 ABZ92421  
EU831572 ACE86491  
EU831485 ACE87172  
AK315618 BAG37986 B2RDN9
AK055786 BAG51575 B1AHC8
AK293439 BAG56943 B4DE32
AK304580 BAG65368 B4E356
CR456492 CAG30378 Q6IC76
CR542219 CAG47015 P12956
CU013089 CAK54520  
CU013377 CAK54819  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens XRCC6 NP_001460 M.musculus Xrcc6 14375 Gene Info NP_034377 84
R.norvegicus Xrcc6 25019   NP_620780 84
A.gambiae AgaP_AGAP002690 1273271   XP_312232 34
A.thaliana KU70 838268   NP_564012 33
S.pombe pku70 2539090   NP_588445 29
N.crassa NCU08290 3878669   XP_962503 28
D.melanogaster Irbp 117419   NP_536773 26
C.elegans cku-70 176546   NP_499438 25
S.cerevisiae YKU70 855328   NP_014011 24

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta