Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HPD, 4-hydroxyphenylpyruvate dioxygenase
Sequence ID:NM_001171993
NM_002150
RefSeqGene ID:NG_016461
Entrez Gene ID:3242
Ensembl ID:ENSG00000158104

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HAWKINSINURIA 
TYROSINEMIA, TYPE III 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q24-qterMitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 122277435 - 122326517

 Exon Info From UCSC:
NM_001171993
NM_002150

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5087393Full LengthBC0242874-hydroxyphenylpyruvate dioxygenase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002141  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001171993 NP_001165464      
NM_002150 NP_002141 P32754 EC 1.13.11.27 Glyoxalase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC024287 AAH24287 P32754 EC 1.13.11.27
DQ892664 ABM83590    
DQ896049 ABM87048    
AK290826 BAF83515 P32754 EC 1.13.11.27
AK057510 BAG51925 P32754 EC 1.13.11.27
X72389 CAA51082 P32754 EC 1.13.11.27

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HPD NP_002141 M.musculus Hpd 15445 Gene Info NP_032303 90
R.norvegicus Hpd 29531   NP_058929 90
A.gambiae AgaP_AGAP004802 1278421   XP_318007 66
D.melanogaster CG11796 40263   NP_730536 63
C.elegans hpd-1 176473   NP_499324 62
N.crassa NCU01830 3872761   XP_956614 57

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)