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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MUS81, MUS81 endonuclease homolog (S. cerevisiae)
Sequence ID:NM_025128
Entrez Gene ID:80198
Ensembl ID:ENSG00000172732

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 65628224 - 65633523

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4135990Full LengthBC009999MUS81 endonuclease homolog (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_079404  

Protein Infomation

NM_025128 NP_079404 Q96NY9 ERCC4

Related Sequences

BC009999 AAH09999 Q96NY9
AF425646 AAL28065 Q96NY9
AK024665 BAB14953 Q96NY9
AK223564 BAD97284 Q53ES5
AK126820 BAG54375 B3KX63
AL353934 CAH56369 Q659C2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MUS81 NP_079404 R.norvegicus Mus81 293678   NP_001020816 82
M.musculus Mus81 71711 Gene Info NP_082153 82
D.melanogaster mus81 31044   NP_569873 45
A.gambiae AgaP_AGAP008836 1279806   XP_319580 43
N.crassa NCU07457 3880057   XP_963908 34
S.cerevisiae MUS81 851994   NP_010674 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)