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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SC5DL, Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
Sequence ID:NM_001024956
RefSeqGene ID:NG_009446
Entrez Gene ID:6309
Ensembl ID:ENSG00000109929

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 121163494 - 121179341

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3537285Full LengthBC012333sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
6049043Full LengthBC050427sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001020127  NP_008849  

Protein Infomation

NM_001024956 NP_001020127 Q6GTM5   Sterol_desat
NM_006918 NP_008849 O75845
EC Sterol_desat

Related Sequences

AF187981 AAF00544 O75845
BC012333 AAH12333 O75845
BC050427 AAH50427 Q6GTM5  
HQ447381 ADQ31867    
AK222686 BAD96406 Q6GTM5  
AK223141 BAD96861 Q6GTM5  
AK312634 BAG35518 Q6GTM5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SC5DL NP_001020127 M.musculus Sc5d 235293 Gene Info NP_766357 84
R.norvegicus Sc5dl 114100   NP_446094 82
N.crassa NCU06207 3879071   XP_962923 56
S.pombe erg3 2542109   NP_593135 55
S.cerevisiae ERG3 850745   NP_013157 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)