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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PPM1D, Protein phosphatase, Mg2+/Mn2+ dependent, 1D
Sequence ID:NM_003620
RefSeqGene ID:NG_023265
Entrez Gene ID:8493
Ensembl ID:ENSG00000170836

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BREAST CANCERAKT1
ATM
BARD1
BRCA1
BRCA2
BRIP1
CASP8
CDH1
CHEK2
CHEK2
HMMR
KRAS
NQO2
NQO2
PALB2
PHB
PIK3CA
PIK3CA
RAD51
RAD54L
RB1CC1
SLC22A18
TP53
TP53
TSG101
XRCC3
XRCC3

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q23.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 58741953 - 58743635

NM_003620 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
16945867755358678246
6959235870088158701109
92410485871121358711337
104912395872525258725442
124014825873395958734201
148331635874035558742035

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3923593Full LengthBC016480protein phosphatase 1D magnesium-dependent, delta isoform
5167004Full LengthBC042418protein phosphatase 1D magnesium-dependent, delta isoform
5260081Full LengthBC060877protein phosphatase 1D magnesium-dependent, delta isoform
5265521Full LengthBC033893protein phosphatase 1D magnesium-dependent, delta isoform

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003611  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003620 NP_003611 O15297 EC 3.1.3.16 PP2C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U78305 AAB61637 O15297 EC 3.1.3.16
BC016480 AAH16480 O15297 EC 3.1.3.16
BC033893 AAH33893 Q8NEA7  
BC042418 AAH42418 Q8IVR6  
BC060877 AAH60877 Q6P991  
BT009780 AAP88782 O15297 EC 3.1.3.16
DQ891047 ABM81973    
EU176552 ABW03353    
AK312902 BAG35748 B2R7A1  
AK299773 BAG61656 B4DSJ4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PPM1D NP_003611 M.musculus Ppm1d 53892 Gene Info NP_058606 90
R.norvegicus Ppm1d 287585   NP_001099295 89

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)