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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PDXK, pyridoxal (pyridoxine, vitamin B6) kinase
Sequence ID:NM_003681
Entrez Gene ID:8566
Ensembl ID:ENSG00000160209

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 45139022 - 45170414

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2989843Full LengthBC005825pyridoxal (pyridoxine, vitamin B6) kinase
3352536Full LengthBC000123pyridoxal (pyridoxine, vitamin B6) kinase
3528340Full LengthBC008008pyridoxal (pyridoxine, vitamin B6) kinase
3528340Full LengthBC041020pyridoxal (pyridoxine, vitamin B6) kinase
4905448Full LengthBC021550pyridoxal (pyridoxine, vitamin B6) kinase
3536686IncompleteBC003651pyridoxal (pyridoxine, vitamin B6) kinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003672  

Protein Infomation

NM_003681 NP_003672 O00764 EC PfkB

Related Sequences

U89606 AAC51233 O00764 EC
BC000123 AAH00123 O00764 EC
BC005825 AAH05825 O00764 EC
BC008008 AAH08008    
BC021550 AAH21550    
BC041020 AAH41020    
AY303972 AAP73047 O00764 EC
AK024977 BAB15048    
AB621819 BAK64155 G1UI32  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PDXK NP_003672 M.musculus Pdxk 216134 Gene Info NP_742146 86
R.norvegicus Pdxk 83578   NP_113957 85
R.norvegicus RGD1566085 361819   XP_342113 83
A.thaliana SOS4 833763   NP_198601 50
D.melanogaster CG34455 39066   NP_996031 50
A.gambiae AgaP_AGAP005929 1276596   XP_315959 47
C.elegans F57C9.1 172101   NP_491463 44
S.cerevisiae BUD16 856683   NP_010885 40
S.pombe SPAC6F6.11c 2542390   NP_593904 40
N.crassa NCU10351 5847068   XP_001728015 39
S.pombe SPCC18.10 2538966   NP_588389 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)