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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PFKFB2, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Sequence ID:NM_001018053
NM_006212
Entrez Gene ID:5208
Ensembl ID:ENSG00000123836

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 207226669 - 207253988

 Exon Info From UCSC:
NM_001018053
NM_006212

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262287Full LengthBC0693856-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
7262299Full LengthBC0695836-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
7262311Full LengthBC0695866-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
7262323Full LengthBC0696006-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
7262370Full LengthBC0693506-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
8327571Full LengthBC1121036-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
8327573Full LengthBC1121056-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
30915381Full LengthBC0750756-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
30915594Full LengthBC0750766-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006203  NP_001018063  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001018053 NP_001018063     PGAM
6PF2K
NM_006212 NP_006203 O60825 EC 2.7.1.105
EC 3.1.3.46
PGAM
6PF2K

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC069350 AAH69350 O60825 EC 2.7.1.105
EC 3.1.3.46
BC069385 AAH69385 O60825 EC 2.7.1.105
EC 3.1.3.46
BC069583 AAH69583 O60825 EC 2.7.1.105
EC 3.1.3.46
BC069586 AAH69586 O60825 EC 2.7.1.105
EC 3.1.3.46
BC069600 AAH69600 O60825 EC 2.7.1.105
EC 3.1.3.46
BC075075 AAH75075 O60825 EC 2.7.1.105
EC 3.1.3.46
BC075076 AAH75076 O60825 EC 2.7.1.105
EC 3.1.3.46
BC112103 AAI12104 O60825 EC 2.7.1.105
EC 3.1.3.46
BC112105 AAI12106 O60825 EC 2.7.1.105
EC 3.1.3.46
AF470623 AAL99386 O60825 EC 2.7.1.105
EC 3.1.3.46
EU334168 ABY59650 B0FLL2  
AB044805 BAB19681 O60825 EC 2.7.1.105
EC 3.1.3.46
AK292883 BAF85572 O60825 EC 2.7.1.105
EC 3.1.3.46
AK295367 BAG58328 B4DI16  
AK302315 BAG63653 B4DY91  
AJ005578 CAA06606 O60825 EC 2.7.1.105
EC 3.1.3.46
CR749442 CAH18280 Q68DE0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PFKFB2 NP_006203 M.musculus Pfkfb2 18640 Gene Info NP_032851 93
R.norvegicus Pfkfb2 24640   NP_001029136 93
S.cerevisiae FBP26 853286   NP_012380 49
N.crassa NCU09347 3875073   XP_958926 49
S.pombe SPAPB17E12.14c 3361378   NP_001018229 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)