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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAT1A, methionine adenosyltransferase I, alpha
Sequence ID:NM_000429
RefSeqGene ID:NG_008083
Entrez Gene ID:4143
Ensembl ID:ENSG00000151224

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:10q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 82031578 - 82035235

NM_000429 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1720798203157682033638
208022138203427582034408
221423968203477282034954
239726158203613182036349
261627598203992882040071
276028728204043582040547
287329958204367182043793
299630738204526782045344
307434198204908882049433

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4341915Full LengthBC018359methionine adenosyltransferase I, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000420  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000429 NP_000420 Q00266 EC 2.5.1.6 S-AdoMet_synt_N
S-AdoMet_synt_M
S-AdoMet_synt_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC018359 AAH18359 Q00266 EC 2.5.1.6
DQ891073 ABM81999    
DQ894256 ABM85182    
D49357 BAA08355 Q00266 EC 2.5.1.6
AK290820 BAF83509 A8K455  
X69078 CAA48822 Q00266 EC 2.5.1.6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAT1A NP_000420 M.musculus Mat1a 11720 Gene Info NP_598414 96
R.norvegicus Mat1a 25331   NP_036992 96
A.thaliana SAM-2 826987   NP_001078345 63
A.thaliana SAM1 839501   NP_171751 63
P.falciparum PfSAMS 813498   XP_001352093 58

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)