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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CYP2C19, Cytochrome P450, family 2, subfamily C, polypeptide 19
Sequence ID:NM_000769
RefSeqGene ID:NG_008384
Entrez Gene ID:1557
Ensembl ID:ENSG00000165841

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CLOPIDOGREL, IMPAIRED RESPONSIVENESS TO 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 96522457 - 96612939

NM_000769 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11689652246296522629
1693319653481496534976
3324819653514696535295
4826429654025596540415
6438199654157796541753
8209619658025296580393
96211499660259396602780
115012919660967396609814
129214729661248996612669

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40080839BC111846cytochrome P450, family 2, subfamily C, polypeptide 19

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000760  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000769 NP_000760   p450

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M61854 AAB59426 P33261 EC 1.14.13.49
EC 1.14.13.80
EC 1.14.13.48
BC111846 AAI11847    
X65962 CAA46778 Q16743  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP2C19 NP_000760 M.musculus Cyp2c65 72303 Gene Info NP_082467 76
R.norvegicus Cyp2c79 293985   XP_219933 76
M.musculus Cyp2c66 69888 Gene Info NP_001011707 75

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)