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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. LRP8, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Sequence ID:NM_001018054
NM_004631
NM_017522
NM_033300
RefSeqGene ID:NG_011517
Entrez Gene ID:7804
Ensembl ID:ENSG00000157193

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MYOCARDIAL INFARCTIONESR1
F13A1
F7
GCLC
GCLM
ITGB3
LGALS2
LTA
MIAT
OLR1
PSMA6
THBD
TNFSF4

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 53712239 - 53793071

 Exon Info From UCSC:
NM_001018054
NM_004631
NM_017522
NM_033300

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6143442Full LengthBC051836low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
3534195IncompleteBC006443low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004622  NP_150643  NP_001018064  NP_059992  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001018054 NP_001018064   EGF
Ldl_recept_a
Ldl_recept_b
EGF_CA
NM_004631 NP_004622 Q14114 EGF
Ldl_recept_a
Ldl_recept_b
EGF_CA
NM_017522 NP_059992   EGF
Ldl_recept_a
Ldl_recept_b
EGF_CA
NM_033300 NP_150643   EGF
Ldl_recept_a
Ldl_recept_b
EGF_CA

Related Sequences

 
mRNAGenPeptSwissProt
BC006443 AAH06443 Q14114
BC051836 AAH51836 Q14114
D50678 BAA09328 Q14114
AK096482 BAG53302 B3KU40
Z75190 CAA99509 Q14114

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LRP8 NP_004622 M.musculus Lrp8 16975 Gene Info NP_001074395 84
R.norvegicus Lrp8 362558   XP_342878 77

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta