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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. TPR, translocated promoter region, nuclear basket protein
Sequence ID:NM_003292
RefSeqGene ID:NG_023284
Entrez Gene ID:7175
Ensembl ID:ENSG00000047410

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 186326406 - 186344864

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4339445IncompleteBC016514translocated promoter region (to activated MET oncogene)
5111447IncompleteBC025177translocated promoter region (to activated MET oncogene)
30528734IncompleteBC094764translocated promoter region (to activated MET oncogene)
100061956BC156389translocated promoter region (to activated MET oncogene)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003283  

Protein Infomation

NM_003292 NP_003283 P12270 TPR_MLP1_2

Related Sequences

U69668 AAB48030 Q99968
BC016514 AAH16514 Q58F23
BC025177 AAH25177 A0PJC9
BC094764 AAH94764 Q504U6
BC156389 AAI56390  
X63105 CAA44819 Q15624
X66397 CAA47021 P12270
Y00672 CAA68681 P12270

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens TPR NP_003283 M.musculus Tpr 108989 Gene Info NP_598541 94
R.norvegicus Tpr 304862   NP_001100655 94
A.gambiae AgaP_AGAP001754 1281420   XP_321328 29
D.melanogaster Mtor 36264   NP_477067 27
N.crassa NCU04059 3873797   XP_957674 26
A.thaliana NUA 844268   NP_001185436 25
S.pombe nup211 2538843   NP_588236 25
S.cerevisiae MLP1 853970   NP_013021 24

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)