Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CARS, cysteinyl-tRNA synthetase
Sequence ID:NM_001014437
NM_001194997
NM_001751
NM_139273
NR_036542
NM_001014438
Entrez Gene ID:833
Ensembl ID:ENSG00000110619

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.5Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 3022275 - 3078614

 Exon Info From UCSC:
NM_001014437
NM_001751
NM_139273
NM_001014438

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3940167Full LengthBC002880cysteinyl-tRNA synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_644802  NP_001014437  NP_001742  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001014437 NP_001014437     tRNA-synt_1e
NM_001194997 NP_001181926      
NM_001751 NP_001742 P49589 EC 6.1.1.16 tRNA-synt_1e
NM_139273 NP_644802     tRNA-synt_1e

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L06845 AAA73901 P49589 EC 6.1.1.16
AF288206 AAG00578 P49589 EC 6.1.1.16
AF288207 AAG00579 P49589 EC 6.1.1.16
BC002880 AAH02880 P49589 EC 6.1.1.16
BT009913 AAP88915 P49589 EC 6.1.1.16
DQ890773 ABM81699    
AB208814 BAD92051 Q59HE5  
AK222614 BAD96334 Q53HG6  
AK289432 BAF82121 A8K067  
AK096313 BAG53256 A8MVQ3  
AK295371 BAG58331 B4DI19  
AK296763 BAG59343 B4DKY1  
AK298514 BAG60719 B4DPV7  
AK302644 BAG63885 P49589 EC 6.1.1.16
BX647906 CAI46108 P49589 EC 6.1.1.16

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CARS NP_001014437 M.musculus Cars 27267 Gene Info NP_038770 90
R.norvegicus Cars 293638   NP_001099789 90
A.gambiae AgaP_AGAP012283 1280406   XP_320253 61
D.melanogaster Aats-cys 36784   NP_611087 60
C.elegans crs-1 171821   NP_491014 56
S.cerevisiae YNL247W 855474   NP_014152 47
S.pombe SPAC29E6.06c 2542721   NP_594564 46
P.falciparum PF10_0149 810307   XP_001347434 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)