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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. AREG, amphiregulin
Sequence ID:NM_001657
Entrez Gene ID:374
Ensembl ID:ENSG00000109321

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 75310852 - 75320727

NM_001657 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12717531085275311122
2725207531225075312498
5217227531476375314964
7238757531609675316248
8769877531826075318371
98812357532047575320722

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4277616Full LengthBC009799amphiregulin
9056881Full LengthBC146953amphiregulin
9056895Full LengthBC146967amphiregulin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001648  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001657 NP_001648 P15514
Q5U026
EGF

Related Sequences

 
mRNAGenPeptSwissProt
M30704 AAA51781 P15514
Q5U026
BC009799 AAH09799 P15514
Q5U026
BC146953 AAI46954 Q5U026
BC146967 AAI46968 Q5U026
BT019866 AAV38669 P15514
Q5U026
DQ892890 ABM83816  
DQ896137 ABM87136  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AREG NP_001648 H.sapiens AREGB 727738 Gene Info XP_001125684 100
R.norvegicus Areg 29183   NP_058819 73
M.musculus Areg 11839 Gene Info NP_033834 72

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)